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Antiochus III the Great (c. 241–187 BC), ruler of the Seleucid Empire
Antiochus III the Great
The 6th ruler of the Seleucid Empire, Antiochus III the Great (Greek: ντίoχoς Μέγας; ca. 241–187 BC, ruled 222–187 BC) Seleucid Greek king ruled over Greater Syria and western Asia towards the end of the 3rd century BC. Rising to the throne at the age of eighteen in 223 BC, his early campaigns against the Ptolemaic Kingdom were unsuccessful, but in the following years Antiochus gained several military victories.
His traditional designation, the Great, reflects an epithet he briefly assumed. He also assumed the title "Basileus Megas" (which is Greek for "Great King"), the traditional title of the Persian kings.
Self-declaring himself the "champion of Greek freedom against Roman domination", Antiochus III waged a war against the Roman Republic in mainland Greece in autumn of 192 BC[4][5] only to be defeated
Antiochus III was a member of the Greek-MacedonianSeleucid dynasty, he was the son of king Seleucus II and Laodice II and was born in 242 BC near Susa in Iran.[10] Antiochus succeeded his brother Seleucus III as the king of the Seleucid Empire.
Antiochus III inherited a disorganized state. Not only had Asia Minor become detached, but the easternmost provinces had broken away, Bactria under the Greek Diodotus of Bactria, and Parthia under the nomad chieftain Arsaces. Soon after Antiochus's accession, Media and Persis revolted under their governors, the brothers Molon and Alexander.
The young king, under the baneful influence of the minister Hermeias, authorised an attack on Ptolemaic Syria instead of going in person to face the rebels. The attack against Egypt of the Ptolemies proved a fiasco, and the generals sent against Molon and Alexander met with disaster. Only in Asia Minor, where the king's cousin, the able Achaeus represented the Seleucid cause, did its prestige recover, driving the Pergamene power back to its earlier limits.
In 221 BC Antiochus at last went east, and the rebellion of Molon and Alexander collapsed which Polybios attributes in part to his following the advice of Zeuxis‎ rather than Hermeias. The submission of Lesser Media, which had asserted its independence under Artabazanes, followed. Antiochus rid himself of Hermeias by assassination and returned to Syria (220 BC). Meanwhile Achaeus himself had revolted and assumed the title of king in Asia Minor. Since, however, his power was not well enough grounded to allow an attack on Syria, Antiochus considered that he might leave Achaeus for the present and renew his attempt on Ptolemaic Syria.

His father
Seleucus III Ceraunus
III Soter, called Seleucus Ceraunus (Greek: Σέλευκος Γ' Σωτρ, Σέλευκος Κεραυνός ca. 243 BC – 223 BC), was a ruler of the Hellenistic Seleucid Kingdom, the eldest son of Seleucus II Callinicus and Laodice II. His birth name was Alexander and was named after his great uncle the Seleucid official Alexander. Alexander changed his name to Seleucus after he succeeded his father as King. After a brief reign of three years (225 BC–223 BC), Seleucus was assassinated in Anatolia by members of his army while on campaign against Attalus I of Pergamon. His official byname "Soter" - Greek: Σωτρ means "Saviour", while his nickname "Ceraunus" - Greek: Κεραυνός means "Thunder".
Early wars against other Hellenistic rulers

The campaigns of 219 BC and 218 BC carried the Seleucid armies almost to the confines of Ptolemaic Kingdom, but in 217 BC Ptolemy IV defeated Antiochus at the Battle of Raphia. This defeat nullified all Antiochus's successes and compelled him to withdraw north of the Lebanon.
In 216 BC Antiochus' army marched into western Anatolia to suppress the local rebellion led by Antiochus' own cousin Achaeus, and had by 214 BC driven him from the field into Sardis. Capturing Achaeus, Antiochus had him executed. The citadel managed to hold out until 213 BC under Achaeus' widow Laodice who surrendered later.
Having thus recovered the central part of Asia Minor (for the Seleucid government had perforce to tolerate the dynasties in Pergamon, Bithynia and Cappadocia) Antiochus turned to recover the outlying provinces of the north and east. He obliged Xerxes of Armenia to acknowledge his supremacy in 212 BC. In 209 BC Antiochus invaded Parthia, occupied the capital Hecatompylus and pushed forward into Hyrcania. The Parthian king Arsaces II apparently successfully sued for peace.
War against Rome and death
Antiochus then moved to Asia Minor, by land and by sea, to secure the coast towns which belonged to the remnants of Ptolemaic overseas dominions and the independent Greek cities. This enterprise earned him the antagonism of the Roman Republic, since Smyrna and Lampsacus appealed to the republic of the west, and the tension grew after Antiochus had in 196 BC established a footing in Thrace. The evacuation of Greece by the Romans gave Antiochus his opportunity, and he now had the fugitive Hannibal at his court to urge him on.
In 192 BC Antiochus invaded Greece with a 10,000 man army, and was elected the commander in chief of the Aetolian League. In 191 BC, however, the Romans under Manius Acilius Glabrio routed him at Thermopylae, forcing him to withdraw to Asia Minor. The Romans followed up their success by invading Anatolia, and the decisive victory of Scipio Asiaticus at Magnesia ad Sipylum (190 BC), following the defeat of Hannibal at sea off Side, delivered Asia Minor into their hands.
By the Treaty of Apamea (188 BC) the Seleucid king abandoned all the country north of the Taurus, which the Roman Republic distributed amongst its local allies. As a consequence of this blow to the Seleucid power, the outlying provinces of the empire, recovered by Antiochus, reasserted their independence. Antiochus mounted a fresh eastern expedition in Luristan, where he died on while pillaging a temple of Bel at Elymaïs, Persia, in 187 BC.[5]
Bactrian campaign and Indian expedition

Coin of Antiochos III.
Year 209 BC saw Antiochus in Bactria, where the Greco-Bactrian king Euthydemus I had supplanted the original rebel. Antiochus again met with success.[12] He was defeated by Antiochus at the Battle of the Arius but after sustaining a famous siege in his capitalBactra (Balkh), Euthydemus obtained an honourable peace by which Antiochus promised Euthydemus' son Demetrius the hand of one of his daughters.[13]
Antiochus next, following in the steps of Alexander, crossed into the Kabul valley, reaching the realm of Indian king Sophagasenus and returned west by way of Seistan and Kerman (206/5). According to Polybius:
"He crossed the Caucasus (Hindu Kush) and descended into India; renewed his friendship with Sophagasenus (Subhashsena in Prakrit) the king of the Indians; received more elephants, until he had a hundred and fifty altogether; and having once more provisioned his troops, set out again personally with his army: leaving Androsthenes of Cyzicus the duty of taking home the treasure which this king had agreed to hand over to him.[13]"
Persia and Coele Syria campaigns

From Seleucia on the Tigris he led a short expedition down the Persian Gulf against the Gerrhaeans of the Arabian coast (205 BC/204 BC). Antiochus seemed to have restored the Seleucid empire in the east, which him the title of "the Great" (Antiochos Megas). In 205/204 BC the infant Ptolemy V Epiphanes succeeded to the Egyptian throne, and Antiochus is said (notably by Polybios) to have concluded a secret pact with Philip V of Macedon for the partition of the Ptolemaic possessions. Under the terms of this pact, Macedon were to receive Egypt's possessions around the Aegean Sea and Cyrene, while Antiochus would annex Cyprus and Egypt.
Once more Antiochus attacked the Ptolemaic province of Coele Syria and Phoenicia, and by 199 BC he seems to have had possession of it before the Aetolian, Scopas, recovered it for Ptolemy. But that recovery proved brief, for in 198 BC Antiochus defeated Scopas at the Battle of Panium, near the sources of the Jordan, a battle which marks the end of Ptolemaic rule in Judea.